In Missouri, I-55 runs from the southeastern part of the state, at the Arkansas border, to St. Louis. Where Interstate 44 merges in and it joins Interstate 64 and Interstate 70 on the Poplar Street Bridge, which crosses the Mississippi River into Illinois.
A section of the I-55 in southern St. Louis County, Missouri has been named the "Rosa Parks Freeway" although the general public still refers to it as I-55.
On July 26th 2007 a small section of I-55 at the St. Louis city/county line was named "Thomas G. Smith Jr. Memorial Freeway".